| Chemotherapeutic treatment of naturally acquired generalized demodicosis. | |
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MedLine Citation:
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PMID: 6684829 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fifty-two dogs naturally parasitized with Demodex canis and having the generalized form of the disease were utilized to evaluate the efficacy and safety of single or multiple topical treatments with a liquid concentrate formulation of amitraz. Ten dogs (5 treated, 5 controls) were utilized to evaluate a single treatment. A single topical treatment with the miticide did not significantly reduce the incidence of dogs with mites, however, significant clinical improvement resulted. Side-effects were not observed after treatment. Forty-two dogs (26 treated, 16 controls) were utilized to evaluate multiple topical treatments with the liquid concentrate. A series of 3-6 treatments was applied topically at 14-day intervals. The dogs treated with the miticide received an average of 4.5 topical treatments. All (100%) of the dogs responded clinically, and the mean rate of improvement at four weeks post-treatment was 99.1%. Most dogs (96.2%) were cleared of mites after 3-6 treatments, and Mitaban did not cause any dermatologic, ocular, or other clinical side-effects. Multiple treatments with the liquid concentrate were highly efficacious and safe for treatment of generalized demodicosis. Control dogs did not improve clinically and retained mite populations. |
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Authors:
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S D Folz; D D Kratzer; R D Conklin; L H Nowakowski; T J Kakuk; D L Rector |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Veterinary parasitology Volume: 13 ISSN: 0304-4017 ISO Abbreviation: Vet. Parasitol. Publication Date: 1983 Aug |
Date Detail:
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Created Date: 1983-11-23 Completed Date: 1983-11-23 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7602745 Medline TA: Vet Parasitol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 85-93 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Animals Dog Diseases / drug therapy* Dogs Insecticides / administration & dosage, therapeutic use* Mite Infestations / drug therapy, veterinary* Toluidines / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Insecticides; 0/Toluidines; 33089-61-1/amitraz |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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