Document Detail

Chemotherapeutic treatment of naturally acquired generalized demodicosis.
MedLine Citation:
PMID:  6684829     Owner:  NLM     Status:  MEDLINE    
Fifty-two dogs naturally parasitized with Demodex canis and having the generalized form of the disease were utilized to evaluate the efficacy and safety of single or multiple topical treatments with a liquid concentrate formulation of amitraz. Ten dogs (5 treated, 5 controls) were utilized to evaluate a single treatment. A single topical treatment with the miticide did not significantly reduce the incidence of dogs with mites, however, significant clinical improvement resulted. Side-effects were not observed after treatment. Forty-two dogs (26 treated, 16 controls) were utilized to evaluate multiple topical treatments with the liquid concentrate. A series of 3-6 treatments was applied topically at 14-day intervals. The dogs treated with the miticide received an average of 4.5 topical treatments. All (100%) of the dogs responded clinically, and the mean rate of improvement at four weeks post-treatment was 99.1%. Most dogs (96.2%) were cleared of mites after 3-6 treatments, and Mitaban did not cause any dermatologic, ocular, or other clinical side-effects. Multiple treatments with the liquid concentrate were highly efficacious and safe for treatment of generalized demodicosis. Control dogs did not improve clinically and retained mite populations.
S D Folz; D D Kratzer; R D Conklin; L H Nowakowski; T J Kakuk; D L Rector
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary parasitology     Volume:  13     ISSN:  0304-4017     ISO Abbreviation:  Vet. Parasitol.     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7602745     Medline TA:  Vet Parasitol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  85-93     Citation Subset:  IM    
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MeSH Terms
Administration, Topical
Dog Diseases / drug therapy*
Insecticides / administration & dosage,  therapeutic use*
Mite Infestations / drug therapy,  veterinary*
Toluidines / administration & dosage,  therapeutic use*
Reg. No./Substance:
0/Insecticides; 0/Toluidines; 33089-61-1/amitraz

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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