Document Detail

Chemotaxonomic identification of single bacteria by micro-Raman spectroscopy: application to clean-room-relevant biological contaminations.
MedLine Citation:
PMID:  15746368     Owner:  NLM     Status:  MEDLINE    
Microorganisms, such as bacteria, which might be present as contamination inside an industrial food or pharmaceutical clean room process need to be identified on short time scales in order to minimize possible health hazards as well as production downtimes causing financial deficits. Here we describe the first results of single-particle micro-Raman measurements in combination with a classification method, the so-called support vector machine technique, allowing for a fast, reliable, and nondestructive online identification method for single bacteria.
Petra Rösch; Michaela Harz; Michael Schmitt; Klaus-Dieter Peschke; Olaf Ronneberger; Hans Burkhardt; Hans-Walter Motzkus; Markus Lankers; Stefan Hofer; Hans Thiele; Jürgen Popp
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  71     ISSN:  0099-2240     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-04     Completed Date:  2005-05-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1626-37     Citation Subset:  IM    
Institut für Physikalische Chemie, Friedrich-Schiller-Universität Jena, Helmholtzweg 4, D-07743 Jena, Germany.
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MeSH Terms
Bacillus / chemistry,  classification
Bacteria / chemistry*,  classification*,  growth & development
Bacterial Typing Techniques / methods*,  statistics & numerical data
Data Interpretation, Statistical
Environment, Controlled*
Environmental Microbiology
Escherichia coli / chemistry,  classification
Micrococcus / chemistry,  classification
Spectrum Analysis, Raman / methods*
Spores, Bacterial / chemistry
Staphylococcus / chemistry,  classification

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