Document Detail


Chemosensors in the nose: guardians of the airways.
MedLine Citation:
PMID:  23280357     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The G-protein-coupled receptor molecules and downstream effectors that are used by taste buds to detect sweet, bitter, and savory tastes are also utilized by chemoresponsive cells of the airways to detect irritants. Here, we describe the different cell types in the airways that utilize taste-receptor signaling to trigger protective epithelial and neural responses to potentially dangerous toxins and bacterial infection.
Authors:
Marco Tizzano; Thomas E Finger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology (Bethesda, Md.)     Volume:  28     ISSN:  1548-9221     ISO Abbreviation:  Physiology (Bethesda)     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101208185     Medline TA:  Physiology (Bethesda)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  51-60     Citation Subset:  IM    
Affiliation:
Department of Cell & Developmental Biology, Rocky Mountain Taste & Smell Center, University of Colorado School of Medicine, Aurora, Colorado.
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