Document Detail

Chemoprophylaxis of early-onset group B streptococcal disease in 1999.
MedLine Citation:
PMID:  10763758     Owner:  NLM     Status:  MEDLINE    
The evolution of the guidelines for selective intrapartum chemoprophylaxis (SIC) of group B streptococcal early-onset disease is reviewed here. To assess the benefits of the risk-based and culture-based strategies for prevention, observational studies since 1996 are summarized. The effect of chorioamnionitis on group B streptococcal early-onset disease, despite SIC, is emphasized. Optimal management remains controversial, and alternative strategies for the selection of women for chemoprophylaxis and for the management of infants are discussed.
S P Gotoff
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in pediatrics     Volume:  12     ISSN:  1040-8703     ISO Abbreviation:  Curr. Opin. Pediatr.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-05-04     Completed Date:  2000-05-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9000850     Medline TA:  Curr Opin Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  105-10     Citation Subset:  IM    
Department of Pediatrics, Rush-Presbyterian St. Luke's Medical Center, Chicago, Illinois 60612-3833, USA.
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MeSH Terms
Age of Onset
Anti-Bacterial Agents / therapeutic use
Infant, Newborn
Infant, Newborn, Diseases / prevention & control
Penicillins / therapeutic use
Pregnancy Complications, Infectious / drug therapy*
Streptococcal Infections / drug therapy*
Streptococcus agalactiae*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Penicillins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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