| Chemonucleolysis in the treatment of sciatica from herniated lumbar disc (author's transl) | |
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MedLine Citation:
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PMID: 7050900 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A proteolytic enzyme was used to dissolve the nucleus pulposus in 140 cases of sciatica from herniated lumbar disc. The results were satisfactory in 75% of 120 patients followed up for more than 6 months. This percentage of success, similar to that obtained with surgical excision of the disc, can only be achieved with a rigourous technique and, more importantly, with strict selection of the patients. Chemonucleolysis is indicated only for patients with unquestionable clinical and radiological evidence of herniated disc, in which case it can be considered as the ultimate medical treatment of sciatica associated with this lesion. No serious complications were observed in our series, but the risk of allergic reaction must be borne in mind. |
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Authors:
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M Benoist; A Deburge; A Rigod; J Busson; J Cauchoix |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: La Nouvelle presse médicale Volume: 11 ISSN: 0301-1518 ISO Abbreviation: Nouv Presse Med Publication Date: 1982 Jun |
Date Detail:
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Created Date: 1982-10-29 Completed Date: 1982-10-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0312552 Medline TA: Nouv Presse Med Country: FRANCE |
Other Details:
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Languages: fre Pagination: 2121-4 Citation Subset: IM |
Vernacular Title:
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La chimionucléolyse dans le traitement des sciatiques discales. 120 observations. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Humans Intervertebral Disk Displacement / complications, drug therapy* Lumbar Vertebrae Male Middle Aged Peptide Hydrolases / therapeutic use* Sciatica / etiology, therapy* Time Factors |
| Chemical | |
Reg. No./Substance:
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EC 3.4.-/Peptide Hydrolases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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