Document Detail


Chemiluminescence micro-flow-injection analysis on a chip.
MedLine Citation:
PMID:  16134229     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chemiluminescence microflow-injection analysis (microFIA) systems on a chip have been developed. The technology of laser ablation was used to fabricate the microchannels on the polymethyl methacrylate (PMMA) chip. The three sampling structure, including double-tee sampling structure, microvalve sampling structure and injection pump with accurate time control, were used. The microcolumn for specific molecular recognition, including molecularly imprinted polymer, enzyme and bacteria, were used to enhance selectivity. These microFIA systems have been applied to clinical analysis, assessment of food safety, in vivo and real-time determination of drugs, and pharmacokinetics studies.
Authors:
Zhujun Zhang; Deyong He; Wei Liu; Yi Lv
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Luminescence : the journal of biological and chemical luminescence     Volume:  20     ISSN:  1522-7235     ISO Abbreviation:  Luminescence     Publication Date:    2005 Jul-Oct
Date Detail:
Created Date:  2005-09-12     Completed Date:  2005-12-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100889025     Medline TA:  Luminescence     Country:  England    
Other Details:
Languages:  eng     Pagination:  377-81     Citation Subset:  IM    
Copyright Information:
Copyright 2005 John Wiley & Sons, Ltd.
Affiliation:
Department of Chemistry, Shaanxi Normal University, XiAn, Shaanxi 710062, People's Republic of China. zzj18@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Biosensing Techniques / instrumentation,  methods
Chemiluminescent Measurements / instrumentation,  methods*
Chromium / blood,  metabolism
Flow Injection Analysis / instrumentation,  methods*
Microchip Analytical Procedures / instrumentation,  methods*
Rabbits
Uric Acid / analysis
Chemical
Reg. No./Substance:
69-93-2/Uric Acid; 7440-47-3/Chromium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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