Document Detail

Chemically induced methaemoglobinaemia in a neonate.
MedLine Citation:
PMID:  1550809     Owner:  NLM     Status:  MEDLINE    
A case of toxic methaemoglobinaemia is presented, which followed the use of a local anaesthetic containing prilocaine (Citanest, Astra Pharmaceuticals Ltd) which was used to provide analgesia prior to the suturing of a facial laceration. Although this complication is well documented, this case is unusual in that it involved a neonate and was not produced by an overdose of prilocaine (the recommendations of the British National Formulary and the product monograph were followed). Explanations for the increased susceptibility of neonates and young infants to methaemoglobinaemia are presented together with the salient clinicopathological features. The diagnostic dilemmas and investigative procedures related to the condition are considered together with the various treatments available.
C J Lloyd
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of oral & maxillofacial surgery     Volume:  30     ISSN:  0266-4356     ISO Abbreviation:  Br J Oral Maxillofac Surg     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-04-28     Completed Date:  1992-04-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405235     Medline TA:  Br J Oral Maxillofac Surg     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  63-5     Citation Subset:  D; IM    
Department of Oral and Maxillofacial Surgery, Royal Shrewsbury Hospital North.
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MeSH Terms
Anesthesia, Local / adverse effects
Infant, Newborn
Methemoglobinemia / chemically induced*
Prilocaine / adverse effects*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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