Document Detail


Chemical sympathectomy with 6-hydroxydopamine in the treatment of primary open-angle glaucoma.
MedLine Citation:
PMID:  1110209     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chemical sympathectomy with 6-hydroxydopamine combined with subsequent topical epinephrine therapy was evaluated with regard to intraocular pressure effects in primary open-angle glaucoma. After chemical sympathectomy intraocular pressure was maintained below 20 mm Hg with 1.0% epinephrine three times daily in 29 of 36 eyes of 25 patients for two to 29 weeks. Chemical sympathectomy combined with epinephrine therapy was most effective in patients whose intraocular pressure had been well controlled with pilocarpine and epinephrine and was less effective in patients whose intraocular pressure had not been controllable with maximum medical therapy prior to the administration of 6-hydroxydopamine. The results of this study suggest that chemical sympathectomy combined with topical epinephrine therapy has considerable clinical value in the medical management of primary open-angle glaucoma.
Authors:
Y Kitazawa; H Nosé; T Horie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  79     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1975 Jan 
Date Detail:
Created Date:  1975-04-11     Completed Date:  1975-04-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  98-103     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Acetazolamide / therapeutic use
Administration, Topical
Amphetamine / diagnostic use
Amphetamines
Epinephrine / administration & dosage,  pharmacology
Glaucoma / drug therapy*
Humans
Hydroxydopamines / therapeutic use*
Intraocular Pressure / drug effects
Iontophoresis
Pilocarpine / therapeutic use
Sympathectomy*
Time Factors
Tonometry, Ocular
Chemical
Reg. No./Substance:
0/Amphetamines; 0/Hydroxydopamines; 300-62-9/Amphetamine; 51-43-4/Epinephrine; 59-66-5/Acetazolamide; 92-13-7/Pilocarpine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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