Document Detail


Chemical peels: what's new and what isn't new but still works well.
MedLine Citation:
PMID:  20024875     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chemical peeling is becoming increasingly popular for the treatment of skin rejuvenation where it can improve damaged skin and fine wrinkles. The basic procedure aims at obtaining a controlled chemical burn of the epidermis and/or dermis. This results in epidermal regeneration and postinflammatory collagen neoformation with remodeling of collagen and elastic fibers and deposition of glycosaminoglycans in the dermis. Various chemicals have been used as peeling agents, of which the most used are the alpha-hydroxy acids, such as glycolic acid, or beta-hydroxy acids, such as salicylic acid. The choice of the compound is linked to the different indications and to the depth of the desired peeling. Phenol is still the best agent for deep peeling but requires specific indications, prescription, and post-peeling care. Combination of different compounds is one innovation in the field of chemical peelings. Further controlled studies are necessary to set up specific guidelines.
Authors:
Gabriella Fabbrocini; Maria Pia De Padova; Antonella Tosti
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-12-18
Journal Detail:
Title:  Facial plastic surgery : FPS     Volume:  25     ISSN:  1098-8793     ISO Abbreviation:  Facial Plast Surg     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-21     Completed Date:  2010-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405303     Medline TA:  Facial Plast Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  329-36     Citation Subset:  D    
Copyright Information:
Thieme Medical Publishers.
Affiliation:
Department of Systematic Pathology, Section of Dermatology, University of Naples Federico II, Naples, Italy.
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MeSH Terms
Descriptor/Qualifier:
Chemexfoliation / methods*
Collagen / drug effects
Elastic Tissue / drug effects
Humans
Hydroxy Acids / therapeutic use
Keratolytic Agents / classification,  therapeutic use*
Phenols / therapeutic use
Regeneration / physiology
Rejuvenation
Skin Aging / pathology
Chemical
Reg. No./Substance:
0/Hydroxy Acids; 0/Keratolytic Agents; 0/Phenols; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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