Document Detail

Chemical methods for degradation of target oligosaccharides using designed light-activatable organic molecules.
MedLine Citation:
PMID:  22378294     Owner:  NLM     Status:  Publisher    
Carbohydrates play crucial roles in a wide range of biological processes, including serious diseases. The development of novel and innovative methods for selective control of specific oligosaccharide functions has attracted much attention in the fields of chemistry, biology, and medicine. In this feature article, the development of novel chemical tools, which can degrade target oligosaccharides by irradiation with a specific wavelength of light under mild conditions without any additives, is introduced. This novel class of photochemical agents promise bright prospects for finding not only molecular-targeted bioprobes for understanding of the structure-activity relationships of oligosaccharides but also novel therapeutic drugs targeting oligosaccharides.
Daisuke Takahashi; Kazunobu Toshima
Related Documents :
15940494 - Postural responses triggered by multidirectional leg lifts and surface tilts.
9108214 - Coupling of fingertip somatosensory information to head and body sway.
8222334 - Use of a computerized postural sway measurement system for assessing workers exposed to...
8186864 - Characteristics of postural stability in patients with aminoglycoside toxicity.
20361244 - Brief report: altered horizontal binding of single dots to coherent motion in autism.
10021504 - Transient change in standing posture after linear treadmill locomotion.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-1
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Ciprofloxacin and Epirubicin Synergistically Induce Apoptosis in Human Urothelial Cancer Cell Lines.
Next Document:  A Non-damaging Method to Analyze the Configuration and Dynamics of Nitrotyrosines in Proteins.