| Chemical inhibitors: a tool for plant cell cycle studies. | |
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MedLine Citation:
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PMID: 10878255 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Synchrony provides a large number of cells at defined points of the cell cycle. Highly synchronised cells are powerful and effective tools for molecular analyses and for studying the biochemical events of the cell cycle in plants. Usually, plant cell suspensions can be synchronised by chemical agents, which arrest the cell cycle by acting on the driving forces of the cell cycle engine such as cyclin-dependent kinase activity, enzymes involved in DNA synthesis or proteolysis of cell cycle regulators or by acting on the cell cycle apparatus (mitotic spindle). The specificity, reversibility and efficiency of each type of cell cycle inhibitor are described and related to their mode of action. |
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Authors:
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S Planchais; N Glab; D Inzé; C Bergounioux |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: FEBS letters Volume: 476 ISSN: 0014-5793 ISO Abbreviation: FEBS Lett. Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-08-02 Completed Date: 2000-08-02 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 78-83 Citation Subset: IM |
Affiliation:
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Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1ZT, UK. sp292@biotech.cam.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Cycle
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drug effects,
physiology* Cyclin-Dependent Kinases / antagonists & inhibitors Enzyme Inhibitors / pharmacology* Plant Physiological Phenomena* Plants / cytology* |
| Chemical | |
Reg. No./Substance:
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0/Enzyme Inhibitors; EC 2.7.11.22/Cyclin-Dependent Kinases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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