| Chemical inactivation of protein toxins on food contact surfaces. | |
| | |
MedLine Citation:
|
PMID: 22690810 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
We compared the kinetics and efficacies of sodium hypochlorite, peracetic acid, phosphoric acid-based detergent, chlorinated alkaline detergent, quaternary ammonium-based sanitizer, and peracetic acid-based sanitizer for inactivating the potential bioterrorism agents ricin and abrin in simple buffers, food slurries (infant formula, peanut butter, and pancake mix), and in dried food residues on stainless steel. The intrinsic fluorescence and cytotoxicity of purified ricin and abrin in buffers decreased rapidly in a pH- and temperature-dependent manner when treated with sodium hypochlorite but more slowly when treated with peracetic acid. Cytotoxicity assays showed rapid and complete inactivation of ricin and crude abrin in food slurries and dried food residues treated 0 - 5 minutes with sodium hypochlorite. Toxin epitopes recognized by ELISA decayed more gradually under these conditions. Higher concentrations of peracetic acid were required to achieve comparable results. Chlorinated alkaline detergent was the most effective industrial agent tested for inactivating ricin in dried food residues. |
| | |
Authors:
|
William H Tolleson; Lauren S Jackson; Odbert A Triplett; Bharat Aluri; Jack C Cappozzo; Katie Banaszewski; Claire W Chang; Kiet T Nguyen |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-6-12 |
Journal Detail:
|
Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
|
Created Date: 2012-6-13 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Molecular characterization of atypical Chlamydia and evidence of their dissemination in different Eu...
Next Document: Minimization of the Impact of Aujeszky's Disease Outbreaks in The Netherlands: A Conceptual Framewor...