| Chemical identification of the sources of commercial Fructus Chebulae. | |
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MedLine Citation:
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PMID: 16042149 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-eight commercial samples of Fructus Chebulae were collected from local herbal markets in Taiwan and were determined to have been derived from Terminalia chebula Retz. and Terminalia chebula Retz. var. parviflora Thwaites, which differ markedly in external appearance. Ten tannin-related constituents [gallic acid (1), chebulic acid (2), punicalagin (4), chebulanin (7), corilagin (8), neochebulinic acid (9), ellagic acid (11), chebulagic acid (12), chebulinic acid (13) and 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (14)] were identified and quantified by HPLC. Samples derived from T. chebula. var. parviflora, which are typically round-shaped, generally contained higher concentrations of 13 and 14 but lower levels of 12 compared with those from T. chebula, which are largely oval-shaped. The ratio of the concentration of 14 to that of 4 may serve as a potential parameter for differentiating samples from the two origins (T. chebula, ratio 0.6 +/- 0.3; T. chebula. var. parviflora, ratio 3.4 +/- 2.2). Levels of the three major bioactive constituents 12-14 were found to provide good references for the quality assessment of Fructus Chebulae. The ratio of the concentration of 12 to that of 14 may offer a guideline for determining quality as well as origin of the drug (lower-grade T. chebula, ratio 12.4 +/- 6.0; medium-grade T. chebula, ratio 8.8 +/- 7.9; higher-grade T. chebula, ratio 3.2 +/- 0.8; T. chebula var. parviflora, ratio 1.6 +/- 0.7). |
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Authors:
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Lih-Jeng Juang; Shuenn-Jyi Sheu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Phytochemical analysis : PCA Volume: 16 ISSN: 0958-0344 ISO Abbreviation: Phytochem Anal Publication Date: 2005 Jul-Aug |
Date Detail:
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Created Date: 2005-07-26 Completed Date: 2005-08-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9200492 Medline TA: Phytochem Anal Country: England |
Other Details:
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Languages: eng Pagination: 246-51 Citation Subset: IM |
Affiliation:
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Department of Chemistry, National Taiwan Normal University, 88, Sec. 4, Tingchow Road, Taipei, Taiwan, Republic of China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carboxylic Acids
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chemistry,
isolation & purification* Drugs, Chinese Herbal / analysis* Fruit / chemistry Taiwan Tannins / chemistry, isolation & purification* Terminalia / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Carboxylic Acids; 0/Drugs, Chinese Herbal; 0/Tannins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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