| Chemical and histochemical studies of normal and diseased human gastrointestinal tract. V. A differential diagnostic method for the histochemical classification of glycoproteins. | |
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MedLine Citation:
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PMID: 2415487 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A differential diagnostic scheme is described for the division of colonic epithelial glycoproteins into eleven histochemically distinct classes. The scheme depends upon the use of seven histochemical techniques which, collectively, permit the differential staining of O-sulphate ester, sialic acid and its side chain O-acyl variants and vicinal diols located on carbohydrate residues other than sialic acids. Elements of the scheme also provide a general approach to the classification of epithelial glycoproteins in anatomic sites other than the colon. Application of the scheme permitted the classification of the epithelial glycoproteins in the mucosa 0.5-5.0 cm from human colonic tumours and provided direct confirmation of previous observations that changes from normal in the relative proportions of either side chain O-acylated sialic acids or sialic acids and O-sulphate esters can occur independently of one another. |
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Authors:
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P E Reid; D A Owen; C W Ramey; W L Dunn; E A Jones; D A Lazosky; E Allen; C M Park; M G Clay |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Histochemical journal Volume: 17 ISSN: 0018-2214 ISO Abbreviation: Histochem. J. Publication Date: 1985 Aug |
Date Detail:
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Created Date: 1985-12-30 Completed Date: 1985-12-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0163161 Medline TA: Histochem J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 891-903 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Colonic Neoplasms
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diagnosis Diagnosis, Differential Digestive System / analysis* Glycoproteins / analysis*, classification Histocytochemistry Humans Intestinal Mucosa / enzymology Staining and Labeling |
| Chemical | |
Reg. No./Substance:
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0/Glycoproteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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