Document Detail

Chemical constituents of aerial parts and roots of Pycnanthemum flexuosum.
MedLine Citation:
PMID:  24632638     Owner:  NLM     Status:  Publisher    
An extract of whole plants of Pycnanthemum flexuosum showed an inhibitory effect on hyaluronidase activity. From an 80% acetone extract of aerial parts, 3-[(3E)-4-phenylbut-3-enoylamino]propionic acid, 3-O-β-D-glucuronopyranosyl- echinocystic acid 28-O-β-D-xylopyranosyl-(1→3)-[3,4-diacetyl-β-D-xylopyranosyl- (1→4)]-a-L-rhamnopyranosyl-(1→2)-a-L-arabinopyranosyl ester, vanillic acid 1-O-[(5-O-syringoyl)-β-D-apiofuranosyl]-(1→2)-β-D-glucopyranoside, and (4S,5R)-4-hydroxy-5-phenyl-tetrahydrofuran-2-one were isolated together with 30 known compounds. Six known compounds were isolated from an 80% acetone extract of roots, and eritrichin was revealed as a hyaluronidase inhibitor in P. flexuosum.
Toshihiro Murata; Mari Nakano; Toshio Miyase; Fumihiko Yoshizaki
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-15
Journal Detail:
Title:  Chemical & pharmaceutical bulletin     Volume:  -     ISSN:  1347-5223     ISO Abbreviation:  Chem. Pharm. Bull.     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-3-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0377775     Medline TA:  Chem Pharm Bull (Tokyo)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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