| Chemical constituents of Talauma arcabucoana (Magnoliaceae): their brine shrimp lethality and antimicrobial activity. | |
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MedLine Citation:
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PMID: 21347974 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A new aporphine alkaloid, (-)-arcabucoine [(6aR)-N-formyl-1,2-methylenedioxy-9,10-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline] 1 was isolated from the leaves of Talauma arcabucoana (Magnoliaceae), along with the known compounds (-)-erythro-saccharinic acid lactone 2 and (-)-shikimic acid 3. Furthermore, the known aporphine alkaloids (-)-dicentrine 4, (-)-nordicentrine 5 and dicentrinone 6 were isolated from the stem bark. The alkaloids 4 and 5 were found to be the most active compounds in a brine shrimp lethality assay. In addition, alkaloids 1, 4 and 5 showed moderate growth inhibition against Staphylococcus aureus and Candida albicans. |
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Authors:
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John Alexander Corredor Barinas; Luis Enrique Cuca Suarez |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-22 |
Journal Detail:
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Title: Natural product research Volume: - ISSN: 1478-6427 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101167924 Medline TA: Nat Prod Res Country: - |
Other Details:
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Languages: ENG Pagination: 1-8 Citation Subset: - |
Affiliation:
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Laboratorio de Investigacion en Productos Naturales Vegetales, Departamento de Quimica, Facultad de Ciencias, Universidad Nacional de Colombia, Bogota, DC, Colombia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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