Document Detail

Chemical constituents of Euphorbia tangutica.
MedLine Citation:
PMID:  22424102     Owner:  NLM     Status:  Publisher    
Sixteen known compounds isolated from the whole plants of Euphorbia tangutica, including phorbol-13-actate (1) previously synthesised and obtained from a natural source for the first time, were evaluated in vitro against a panel of human cancer cell lines using the MTT method. Among them, ergosterol (6) exhibited significant cytotoxic activity against HL-60 cell line with an IC(50) value of 3.3 µM, and 3β,5α-dihydroxy-15β-cinnamoyloxy-14-oxolathyra-6 Z,12 E-diene (7) also displayed moderate activity.
Ben-Yin Zhang; Huan Wang; Xiao-Dong Luo; Zhi-Zhi Du; Hai-Feng Wu; Jian-Wei Shen; Xiao-Feng Zhang
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-16
Journal Detail:
Title:  Natural product research     Volume:  -     ISSN:  1478-6427     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101167924     Medline TA:  Nat Prod Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
a Northwest Institute of Plateau Biology, Chinese Academy of Sciences , Xining 810008 , China.
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