| Chemical composition and anti-stress effects of yeast hydrolysate. | |
| | |
MedLine Citation:
|
PMID: 20041782 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In the present study, the anti-stress effects of yeast hydrolysate (YH) were investigated. The YH consisted of crude carbohydrate (23.6%) and crude protein (68.3%) with low contents of crude ash (3.1%) and crude fat (0.3%). Also, acidic amino acids (glutamic acid + aspartic acid) were present in large quantities (14.2 and 5.0 mol%, respectively). Pronase digestion had little effect on the affinity of the YH on 5-hydroxytryptamine (serotonin) and norepinephrine transporters, whereas NaIO(4) oxidation of the hydrolysate decreased the affinity by about 10% at 1,000 microg/mL, indicating that the periodate-labile carbohydrate moiety played a leading role in the affinity effects of the carbohydrate in YH. As a result of brain mapping after the administration of the YH for 3 days in human subjects, a symmetrical distribution of theta and alpha waves in the central and parietal lobes was observed. This brain mapping pattern of theta and alpha wave distribution appears in a psychologically stable state. The YH groups showed improvements in Beck Depression Inventory and Beck Anxiety Inventory scores after YH administration for 2 weeks. Treatment also seemed to have a more significant (P < .05) impact on the somatic manifestations of anxiety as indexed by the Beck Anxiety Inventory scores. Food materials used as a source of YH have been found to be associated with increases in alertness and adaptation to stress. |
| | |
Authors:
|
Hyun-Sun Lee; Eun Young Jung; Hyung Joo Suh |
Publication Detail:
|
Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: Journal of medicinal food Volume: 12 ISSN: 1557-7600 ISO Abbreviation: J Med Food Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2009-12-31 Completed Date: 2010-03-05 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9812512 Medline TA: J Med Food Country: United States |
Other Details:
|
Languages: eng Pagination: 1281-5 Citation Subset: IM |
Affiliation:
|
Research Institute of Health Sciences, Korea University, Seoul, Republic of Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anxiety / drug therapy Brain Mapping Female Humans Hydrolysis Male Middle Aged Saccharomyces cerevisiae / chemistry* Stress, Psychological / drug therapy*, psychology Yeast, Dried / administration & dosage*, chemistry |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Carica papaya (Paw-Paw) unripe fruit may be beneficial in ulcer.
Next Document: Antioxidant properties of raisins (Vitis vinifera L.).