Document Detail


Chemical and biological consequences of beta-decay. Part 2.
MedLine Citation:
PMID:  339258     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In Part 1 of this article physical and chemical effects of beta-decay in labelled molecules were reviewed and their potential importance for breaking predetermined and specific bonds were pointed out. After incorporation of labelled biomolecules in living systems, such as viruses, phages or cells, the radioactive decay of the label alters the biological behaviour of the system, in the extreme case causing loss of the ability to reproduce, the extent of these consequences depending strongly on the type of radioisotope. Now Part 2 includes a brief discussion of biological effects associated with beta-decay emphasizing the relative importance of local transmutation and internal radiation effects from the decay of 3H, 14C, 32P, 33P, 35S and 125I. Attempt is also made, whenever possible at the present stage of understanding, to correlate biological effects with chemical processes on a molecular level.
Authors:
A Halpern; G Stöcklin
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Radiation and environmental biophysics     Volume:  14     ISSN:  0301-634X     ISO Abbreviation:  Radiat Environ Biophys     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0415677     Medline TA:  Radiat Environ Biophys     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  257-74     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carbon Radioisotopes
Carcinoma, Ehrlich Tumor
Cell Nucleus / radiation effects
DNA / radiation effects
Idoxuridine
Iodine Radioisotopes
Phosphorus Radioisotopes
Radiation, Ionizing*
Sulfur Radioisotopes
Tritium
Chemical
Reg. No./Substance:
0/Carbon Radioisotopes; 0/Iodine Radioisotopes; 0/Phosphorus Radioisotopes; 0/Sulfur Radioisotopes; 10028-17-8/Tritium; 54-42-2/Idoxuridine; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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