Document Detail


Chemical and biochemical microsensors in silicon for the clinical on-line monitoring.
MedLine Citation:
PMID:  12451819     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Miniaturised chemosensors and biosensors for applications in clinical diagnostics and biomedical fields can be fabricated in silicon with high reproducibility using the containment technology. They are characterised by excellent durability of the sensitive membranes. Meanwhile, there are sensors available for a variety of relevant medically parameters such as pH, the blood electrolytes sodium, calcium, potassium, and the blood metabolites glucose and lactate. The miniaturised sensors provide the opportunity to develop product solutions with minimal sampling volume requirements for the "Point of Care (POC)" sector through the combination of innovative microtechnical components. Two examples are presented, such microsystems have been implemented for the medical applications of "Blood Monitoring" and "Glucose Monitoring".
Authors:
A Scheipers; H Hinkers; O Wassmus; Ch Sundermeier; B Ross
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomedizinische Technik. Biomedical engineering     Volume:  47 Suppl 1 Pt 1     ISSN:  0013-5585     ISO Abbreviation:  Biomed Tech (Berl)     Publication Date:  2002  
Date Detail:
Created Date:  2002-11-27     Completed Date:  2003-03-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1262533     Medline TA:  Biomed Tech (Berl)     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  209-12     Citation Subset:  IM    
Affiliation:
Institut für Chemo- und Biosensorik e.V., Deutschland. a.scheipers@icb-online.de
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MeSH Terms
Descriptor/Qualifier:
Blood Chemical Analysis / instrumentation
Blood Glucose / analysis
Electrolytes / blood
Humans
Hydrogen-Ion Concentration
Microelectrodes*
Monitoring, Physiologic / instrumentation*
Online Systems / instrumentation*
Point-of-Care Systems
Signal Processing, Computer-Assisted / instrumentation*
Silicon*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Electrolytes; 7440-21-3/Silicon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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