Document Detail


Chemical aversion therapy in the treatment of cocaine dependence as part of a multimodal treatment program: treatment outcome.
MedLine Citation:
PMID:  2313768     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A pilot feasibility study of chemical aversion therapy in the treatment of cocaine dependence as part of a multimodal treatment program was conducted at the Schick Shadel Hospital of Santa Barbara. Twenty (20) patients (9 treating for cocaine only and 11 treating for cocaine/alcohol), who primarily snorted cocaine, completed a program which included chemical aversion therapy to develop a conditioned aversion to the sight, smell, and taste of a cocaine substitute (tetracaine, mannitol, and quinine with Psychem. Ninety-five (95) percent of patients were followed up in six months with a total abstinence rate from cocaine of 56% (78% current abstinence of at least 30 days prior to follow-up) in the cocaine only group and total abstinence from cocaine of 70% (also 70% current abstinence) for the cocaine/alcohol group. Ninety (90) percent were followed up at 18 months. Thirty eight (38) percent of the cocaine only group had been totally abstinent (75% were currently abstinent). Fifty (50) percent of the cocaine/alcohol group had been totally abstinent (80% were currently abstinent). Validation of results was obtained from "significant others" for 90% of patients.
Authors:
P J Frawley; J W Smith
Related Documents :
22143708 - A prospective, randomized, triple-blind comparison of articaine and bupivacaine for max...
20374628 - Does the number of free nicotine patches given to smokers calling a quitline influence ...
24551648 - Conjunctival autograft in primary and recurrent pterygium: a study.
23538328 - Mdct angiography to evaluate the therapeutic effect of ptve for esophageal varices.
16143228 - A comparison of raloxifene and calcium plus vitamin d on vaginal atrophy after disconti...
9719168 - Cyclosporin for the prevention of disease reactivation in relapsing anca-associated vas...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of substance abuse treatment     Volume:  7     ISSN:  0740-5472     ISO Abbreviation:  J Subst Abuse Treat     Publication Date:  1990  
Date Detail:
Created Date:  1990-04-26     Completed Date:  1990-04-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8500909     Medline TA:  J Subst Abuse Treat     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  21-9     Citation Subset:  IM    
Affiliation:
Schick Shadel Hospital, Santa Barbara, California 93105.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Administration, Inhalation
Adolescent
Adult
Alcoholism / rehabilitation*
Aversive Therapy / methods*
Cocaine*
Combined Modality Therapy
Emetine / therapeutic use
Female
Follow-Up Studies
Humans
Injections, Intramuscular
Male
Pilot Projects
Substance-Related Disorders / rehabilitation*
Tetracaine / therapeutic use*
Chemical
Reg. No./Substance:
483-18-1/Emetine; 50-36-2/Cocaine; 94-24-6/Tetracaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Improvement in psychological functioning among drug abusers: inpatient treatment compared to outpati...
Next Document:  Rubella immunity in chemically dependent adolescent females.