| Chemical aversion therapy in the treatment of cocaine dependence as part of a multimodal treatment program: treatment outcome. | |
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MedLine Citation:
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PMID: 2313768 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A pilot feasibility study of chemical aversion therapy in the treatment of cocaine dependence as part of a multimodal treatment program was conducted at the Schick Shadel Hospital of Santa Barbara. Twenty (20) patients (9 treating for cocaine only and 11 treating for cocaine/alcohol), who primarily snorted cocaine, completed a program which included chemical aversion therapy to develop a conditioned aversion to the sight, smell, and taste of a cocaine substitute (tetracaine, mannitol, and quinine with Psychem. Ninety-five (95) percent of patients were followed up in six months with a total abstinence rate from cocaine of 56% (78% current abstinence of at least 30 days prior to follow-up) in the cocaine only group and total abstinence from cocaine of 70% (also 70% current abstinence) for the cocaine/alcohol group. Ninety (90) percent were followed up at 18 months. Thirty eight (38) percent of the cocaine only group had been totally abstinent (75% were currently abstinent). Fifty (50) percent of the cocaine/alcohol group had been totally abstinent (80% were currently abstinent). Validation of results was obtained from "significant others" for 90% of patients. |
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Authors:
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P J Frawley; J W Smith |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of substance abuse treatment Volume: 7 ISSN: 0740-5472 ISO Abbreviation: J Subst Abuse Treat Publication Date: 1990 |
Date Detail:
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Created Date: 1990-04-26 Completed Date: 1990-04-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8500909 Medline TA: J Subst Abuse Treat Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 21-9 Citation Subset: IM |
Affiliation:
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Schick Shadel Hospital, Santa Barbara, California 93105. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Inhalation Adolescent Adult Alcoholism / rehabilitation* Aversive Therapy / methods* Cocaine* Combined Modality Therapy Emetine / therapeutic use Female Follow-Up Studies Humans Injections, Intramuscular Male Pilot Projects Substance-Related Disorders / rehabilitation* Tetracaine / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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483-18-1/Emetine; 50-36-2/Cocaine; 94-24-6/Tetracaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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