Document Detail


Chemical composition of endemic Scorzonera sandrasica and studies on the antimicrobial activity against multiresistant bacteria.
MedLine Citation:
PMID:  20438328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study describes the antimicrobial activity and chemical composition of Scorzonera sandrasica Hartvig et Strid (Family Asteraceae), endemic to Turkey. The antimicrobial activity of the hexane, chloroform, ethyl acetate, and ethanol extracts of the aerial parts of S. sandrasica was evaluated against microorganisms, including multiresistant bacteria, using a paper disc diffusion method. The chemical composition of the chloroform extract of the plant was determined by gas chromatography and gas chromatography-mass spectrometry. The major compounds of the chloroform extract of the plant were caryophyllene oxide (19.7%), manoyl oxide (16.5%), and manool (11.3%), respectively. The extracts had antibacterial activity; however, no antifungal activity was observed against the two fungi. In particular, the ethanol and chloroform extracts exhibited significant activity against multiresistant strains of Stenotrophomonas maltophilia.
Authors:
Aysel Ugur; Nurdan Sarac; Ozgur Ceylan; M Emin Duru; Yavuz Beyatli
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of medicinal food     Volume:  13     ISSN:  1557-7600     ISO Abbreviation:  J Med Food     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-04     Completed Date:  2010-08-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812512     Medline TA:  J Med Food     Country:  United States    
Other Details:
Languages:  eng     Pagination:  635-9     Citation Subset:  IM    
Affiliation:
Department of Biology, Faculty of Science and Arts, Mugla University, Mugla, Turkey. ayselugur@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / analysis,  isolation & purification,  pharmacology*
Bacteria / drug effects*
Disk Diffusion Antimicrobial Tests
Drug Resistance, Multiple, Bacterial*
Plant Extracts / analysis,  isolation & purification,  pharmacology*
Scorzonera / chemistry*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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