Document Detail

Chemical colitis due to glutaraldehyde: case series and review of the literature.
MedLine Citation:
PMID:  19104938     Owner:  NLM     Status:  In-Process    
Chemical colitis can occur as a result of accidental contamination of endoscopes or by intentional/accidental administration of enemas containing various chemicals.We present three cases of glutaraldehyde induced colitis and review the cases in the literature. Glutaraldehyde induced colitis presents clinically with severe abdominal pain, bloody and mucoid diarrhea, rectal bleeding, and tenesmus 48-72 h after colonoscopy. Endoscopic findings are nonspecific and mimic ischemic colitis, inflammatory bowel disease, and infectious colitis. The timing of symptoms and the knowledge that glutaraldehyde is a chemical irritant to colonic mucosa is important for the diagnosis. The treatment is mainly supportive but sometimes necessitates mesalamine, prednisolone, or metronidazole and the resolution is rapid. In endoscopy units, strict adherence to published disinfection protocols is very important and the cleaning, rinsing and drying protocols also deserve the same attention.
Emel Ahishali; Oya Uygur-Bayramiçli; Can Dolapçioğlu; Reşat Dabak; Alperen Mengi; Aygün Işik; Elvan Ermiş
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  54     ISSN:  1573-2568     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2011-04-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2541-5     Citation Subset:  AIM; IM    
Copyright Information:
© Springer Science+Business Media, LLC 2008
Department of Gastroenterology, Kartal State Hospital, No: 55/8 Bostanci, 34744 Istanbul, Turkey.
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