Document Detail


Charged pair current networks in bioenergetics.
MedLine Citation:
PMID:  4528466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The operation of bioenergetic systems is postulated to be based on charged pair networks. The basic elements of the networks are pairs of opposite charges accompanied by conformational changes of the protein medium. The elementary events are the separation and recombination of charged pairs and partner exchange between two such pairs. The last event makes the construction of networks possible and provides for the flexibility of coupling modes in mitochondria. Bioenergetic systems appear to use electricity in a hitherto unsuspected way. The networks are constructed entirely on electrostatic principles. The possibility of generalization to include mechanical elements is discussed.
Authors:
G Kemeny
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  71     ISSN:  0027-8424     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  1974 Aug 
Date Detail:
Created Date:  1974-12-16     Completed Date:  1974-12-16     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  3064-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Electricity
Energy Transfer*
Enzymes
Macromolecular Substances
Mitochondria
Models, Biological*
Protein Conformation
Chemical
Reg. No./Substance:
0/Enzymes; 0/Macromolecular Substances
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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