| Charge-transfer chromatographic study on the interaction of amino acids with ethoxylated stearic acid surfactants. | |
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MedLine Citation:
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PMID: 8130634 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The interaction of amino acids with ethoxylated stearic acid nonionic surfactants was studied by charge-transfer reversed-phase thin-layer chromatography and the relative strength of interaction was calculated. In the majority of cases the surfactant has a negligible effect on the hydrophobicity of amino acids. Only the binding of Asn, Cys, Gln, Leu, Lys, Met, Nle, Phe, Ser, Trp and Tyr to the surfactants was observed, however, the strength of interaction was fairly low. Stepwise regression analysis proved that the electronic parameters of the amino acids have the highest impact on the strength of interaction. This finding supports the hypothesis that the binding of ethoxylated stearic acid nonionic surfactants to proteins involves more than one amino acid residues and that the hydrophilic forces have a considerable impact on the interaction. |
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Authors:
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T Cserháti |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biomedical chromatography : BMC Volume: 8 ISSN: 0269-3879 ISO Abbreviation: Biomed. Chromatogr. Publication Date: 1994 Jan-Feb |
Date Detail:
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Created Date: 1994-04-21 Completed Date: 1994-04-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8610241 Medline TA: Biomed Chromatogr Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 45-8 Citation Subset: IM |
Affiliation:
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Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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metabolism* Chromatography, Thin Layer / methods* Regression Analysis Stearic Acids / metabolism* Surface-Active Agents / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Stearic Acids; 0/Surface-Active Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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