Document Detail

Characterizing the assembly behaviors of human amylin: a perspective derived from C-terminal variants.
MedLine Citation:
PMID:  23146899     Owner:  NLM     Status:  Publisher    
The differences in the C-terminal domains of human amylin peptide variants initiate different aggregation processes and differences in the composition of the aggregates by affecting the hydrophobic cores, conformations, and intra-sheet interactions of the peptides, which have distinct effects on the cytotoxicity of the peptides.
Mei-Sha Chen; De-Sheng Zhao; Ye-Ping Yu; Wei-Wei Li; Yong-Xiang Chen; Yu-Fen Zhao; Yan-Mei Li
Related Documents :
20025949 - Impact of amino acid replacements on in vitro permeation enhancement and cytotoxicity o...
19664999 - Nanoscale analysis of supported lipid bilayers using atomic force microscopy.
19244249 - Dynamic alpha-helix structure of micelle-bound human amylin.
23528099 - Synergistic insertion of antimicrobial magainin-family peptides in membranes depends on...
1721059 - Localization of an apolipoprotein a-i epitope critical for activation of lecithin-chole...
9059499 - Fluorescence studies on the interaction of a synthetic signal peptide and its analog wi...
6085079 - Studies on immunological properties of fibroin heavy and light chains.
9531289 - Epitope-specific antibody response to ige by mimotope immunization.
7853539 - Contribution of conserved amino acids in mediating the interaction between ebna2 and cb...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-12
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Genomic evidence for elevated mutation rates in highly expressed genes.
Next Document:  Expression of Nogo-A Is Decreased with Increasing Gestational Age in the Human Fetal Brain.