Document Detail


Characterizing the assembly behaviors of human amylin: a perspective derived from C-terminal variants.
MedLine Citation:
PMID:  23146899     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The differences in the C-terminal domains of human amylin peptide variants initiate different aggregation processes and differences in the composition of the aggregates by affecting the hydrophobic cores, conformations, and intra-sheet interactions of the peptides, which have distinct effects on the cytotoxicity of the peptides.
Authors:
Mei-Sha Chen; De-Sheng Zhao; Ye-Ping Yu; Wei-Wei Li; Yong-Xiang Chen; Yu-Fen Zhao; Yan-Mei Li
Related Documents :
8417379 - Mutations in the putative lipid-interaction domain of complement c9 result in defective...
18428039 - Structural-dynamical properties of the transmembrane segment vi of the mitochondrial ox...
16990839 - Apolipoprotein a-i mimetic peptides and their role in atherosclerosis prevention.
22781499 - Liver uptake of radiolabeled targeting proteins and peptides: considerations for target...
8784189 - Design of membrane-inserting peptides: spectroscopic characterization with and without ...
16305499 - Interactions of primary amphipathic cell penetrating peptides with model membranes: con...
16042389 - Phosphothr peptide binding globally rigidifies much of the fha domain from arabidopsis ...
11226239 - Recent improvements in prediction of protein structure by global optimization of a pote...
2304629 - Release of calcitonin gene-related peptide induced by capsaicin in the vascularly perfu...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-12
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. liym@mail.tsinghua.edu.cn.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Genomic evidence for elevated mutation rates in highly expressed genes.
Next Document:  Expression of Nogo-A Is Decreased with Increasing Gestational Age in the Human Fetal Brain.