| Characterization of transposon Tn1549, conferring VanB-type resistance in Enterococcus spp. | |
| | |
MedLine Citation:
|
PMID: 10846226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Transfer of VanB-type resistance to glycopeptides among enterococci has been reported to be associated with the movement of large chromosomal genetic elements or of plasmids. The authors report the characterization of the 34 kb transposon Tn1549 borne by a plasmid related to pAD1 and conferring vancomycin resistance in clinical isolates of Enterococcus spp. Tn1549 contained 30 ORFs and appeared to be organized like the Tn916 family of conjugative transposons into three functional regions: (i) the right end, implicated in the excision-integration process; (ii) the central part, in which the vanB2 operon replaces the tet(M) gene; and (iii) the left extremity, in which eight of the 18 ORFs could be implicated in the conjugative transfer. |
| | |
Authors:
|
F Garnier; S Taourit; P Glaser; P Courvalin; M Galimand |
Related Documents
:
|
947886 - Inheritance of nocardiophage phi ec in matings of nocardial lysogens. 2504476 - Plasmid transfer and plasmid-mediated genetic exchange in brucella abortus. 5340306 - Drug resistance of enteric bacteria. ix. distribution of r factors in gram-negative bac... 4552226 - Incompatibility of integrated sex factors in double male strains of escherichia coli. 9449946 - Pneumococci causing invasive disease in britain 1982-1990. 21750666 - Predicting the epidemic sizes of influenza a/h1n1, a/h3n2, and b: a statistical method. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Microbiology (Reading, England) Volume: 146 ( Pt 6) ISSN: 1350-0872 ISO Abbreviation: Microbiology (Reading, Engl.) Publication Date: 2000 Jun |
Date Detail:
|
Created Date: 2000-08-07 Completed Date: 2000-08-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9430468 Medline TA: Microbiology Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 1481-9 Citation Subset: IM |
Affiliation:
|
Unité des Agents Antibactériens and Laboratoire de Génomique des Micro-organismes Pathogènes, Institut Pasteur, 75724 Paris Cedex 15, France. |
| Data Bank Information | |
Bank Name/Acc. No.:
|
GENBANK/AJ192329 |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bacterial Proteins
/
genetics* Base Sequence Conjugation, Genetic DNA Primers / genetics DNA Transposable Elements / genetics* Enterococcus faecalis / drug effects*, genetics*, isolation & purification Enterococcus faecium / drug effects*, genetics*, isolation & purification Genes, Bacterial Molecular Sequence Data Multigene Family Open Reading Frames Operon Plasmids / genetics Vancomycin Resistance / genetics* |
| Chemical | |
Reg. No./Substance:
|
0/Bacterial Proteins; 0/DNA Primers; 0/DNA Transposable Elements; 0/VanB protein, Enterococcus |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Genetic linkage of the vanB2 gene cluster to Tn5382 in vancomycin-resistant enterococci and characte...
Next Document: The wonderful history of neonatal screening