Document Detail

Characterization of subcortical structures during deep brain stimulation utilizing support vector machines.
MedLine Citation:
PMID:  22256184     Owner:  NLM     Status:  MEDLINE    
In this paper we discuss an efficient methodology for the characterization of Microelectrode Recordings (MER) obtained during deep brain stimulation surgery for Parkinson's disease using Support Vector Machines and present the results of a preliminary study. The methodology is based in two algorithms: (1) an algorithm extracts multiple computational features from the microelectrode neurophysiology, and (2) integrates them in the support vector machines algorithm for classification. It has been applied to the problem of the recognition of subcortical structures: thalamus nucleus, zona incerta, subthalamic nucleus and substantia nigra. The SVM (support vector machines) algorithm performed quite well achieving 99.4% correct classification. In conclusion, the use of a computer-based system, like the one described in this paper, is intended to avoid human subjectivity in the localization of the subcortical structures and mainly the subthalamic nucleus (STN) for neurostimulation.
P Guillén; F Martínez-de-Pisón; R Sánchez; M Argáez; L Velázquez
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-05-31     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7949-52     Citation Subset:  IM    
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MeSH Terms
Cerebral Cortex / pathology*
Deep Brain Stimulation / methods*
Middle Aged
Reproducibility of Results
Support Vector Machines*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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