Document Detail


Characterization of spontaneous recurrent ventricular arrhythmias detected by electrogram-storing defibrillators in sudden cardiac death survivors with no inducible ventricular arrhythmias at baseline electrophysiologic testing.
MedLine Citation:
PMID:  8701887     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This retrospective study characterized the recurring ventricular arrhythmias with an electrogram-storing defibrillator in survivors of sudden cardiac death who had no inducible sustained ventricular arrhythmias at baseline electrophysiologic testing (EPS). The study group was composed of 24 selected patients with documented ventricular fibrillation (VF) without need of revascularization or chronic antiarrhythmic therapy. The EPS protocol usually consisted of three extrastimuli at two drive cycles at two right ventricular sites. Nonischemic cardiomyopathy was the most frequent structural abnormality (n = 11) followed by coronary artery disease (n = 7). The mean ejection fraction was 0.37 +/- 0.13. Cardiac status did not appear to change during a mean follow-up period of 16.4 +/- 12.5 months, and eight (33%) patients received appropriate shocks in that time period. On the basis of intracardiac electrograms, 7 (88%) patients experienced VF and 1 (12%) patient had ventricular tachycardia as the first recurring arrhythmia. Four patients had additional recurrences and all were VF episodes. VF was usually present from the onset of the arrhythmia. In addition, 9 (38%) patients had nonsustained ventricular arrhythmias that were solely VF in 6 (67%). In conclusion, VF of sudden onset was the most frequent recurring sustained ventricular arrhythmia in this group.
Authors:
S Zaim; B Zaim; J Rottman; I Mendoza; N Nasir; A Pacifico
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American heart journal     Volume:  132     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-09-03     Completed Date:  1996-09-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  274-9     Citation Subset:  AIM; IM    
Affiliation:
Hahnemann University Hospital, Philadelphia, Pa, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Arrhythmias, Cardiac / diagnosis,  physiopathology*,  therapy
Death, Sudden, Cardiac*
Defibrillators, Implantable*
Electrocardiography*
Female
Humans
Male
Middle Aged
Recurrence
Retrospective Studies
Survivors
Tachycardia, Ventricular / diagnosis,  physiopathology
Ventricular Fibrillation / diagnosis,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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