Document Detail


Characterization of single-file flow through human retinal parafoveal capillaries using an adaptive optics scanning laser ophthalmoscope.
MedLine Citation:
PMID:  21483603     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Adaptive Optics Scanning Laser Ophthalmoscopy was used to noninvasively acquire videos of single-file flow through live human retinal parafoveal capillaries. Videos were analyzed offline to investigate capillary flow dynamics. Certain capillaries accounted for a clear majority of leukocyte traffic (Leukocyte-Preferred-Paths, LPPs), while other capillaries primarily featured plasma gap flow (Plasma-Gap-Capillaries, PGCs). LPPs may serve as a protective mechanism to prevent inactivated leukocytes from entering exchange capillaries, and PGCs may serve as relief valves to minimize flow disruption due to the presence of a leukocyte in a neighboring LPP.
Authors:
Johnny Tam; Pavan Tiruveedhula; Austin Roorda
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Publication Detail:
Type:  Journal Article     Date:  2011-03-02
Journal Detail:
Title:  Biomedical optics express     Volume:  2     ISSN:  2156-7085     ISO Abbreviation:  Biomed Opt Express     Publication Date:  2011  
Date Detail:
Created Date:  2011-04-12     Completed Date:  2011-07-14     Revised Date:  2011-07-28    
Medline Journal Info:
Nlm Unique ID:  101540630     Medline TA:  Biomed Opt Express     Country:  United States    
Other Details:
Languages:  eng     Pagination:  781-93     Citation Subset:  -    
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