| Characterization of rat hepatoma glucosamine 6-phosphate synthase and its relation to liver and fetal forms. | |
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MedLine Citation:
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PMID: 445481 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Glucosamine 6-phosphate synthase (EC 5.3.1.19) purified from various rat tissues by a procedure involving chromatography on diethylaminoethyl Sephadex and hydroxylapatite were characterized by means of isoelectric focusing. The non-hepatic isozyme, previously reported to be present in Yoshida sarcoma, has a pI of 4.1 and is distinguished from the hepatic isozyme, with a pI of 5.0. The pI 4.1 form is the major one in all of the fast-growing, transplantable hepatomas studied. Although not detectable in 19-day fetal liver or normal adult liver, the pI 4.1 form has been observed in the whole 12-day fetus and adult brain as almost the sole form of glucosamine 6-phosphate synthase. |
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Authors:
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T Miyagi; S Tsuiki |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Cancer research Volume: 39 ISSN: 0008-5472 ISO Abbreviation: Cancer Res. Publication Date: 1979 Jul |
Date Detail:
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Created Date: 1979-09-01 Completed Date: 1979-09-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2984705R Medline TA: Cancer Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2779-82 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain / enzymology Carbohydrate Epimerases / metabolism* Fetus Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) / metabolism* Isoelectric Focusing Liver / enzymology* Liver Neoplasms, Experimental / enzymology* Male Rats |
| Chemical | |
Reg. No./Substance:
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EC 2.6.1.16/Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); EC 5.1.3.-/Carbohydrate Epimerases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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