Document Detail


Characterization of normal and abnormal canine superficial lymph nodes using gray-scale B-mode, color flow mapping, power, and spectral Doppler ultrasonography: a multivariate study.
MedLine Citation:
PMID:  16250399     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to characterize the ultrasonographic patterns of normal superficial lymph nodes and to evaluate whether ultrasonography can help discriminate between different lymphadenopathies (reactive, lymphoma, and metastases) in dogs. Three hundred and eighteen superficial lymph nodes in 142 dogs were studied by B-mode, color flow mapping, power, and spectral Doppler ultrasonography. Size, echogenicity, nodal border definition, presence of a nodal hilus, acoustic enhancement and distribution of vascular flow, as well as perfusion indices were measured. Multivariate statistics using discriminant analysis was used to determine which parameters can be used to predict the diagnosis of the lymph node. The size of the lymph node, distribution of vascular flow within the lymph node, and pulsatility index (PI) in combination gave a classification error of 23% for the four groups of lymph nodes. This was improved to 11% if the nodes were divided into two groups: benign and malignant. There was a significant difference in resistive index (RI) and PI between benign and malignant nodes. Cut-off values were determined using receiver operator curves, 0.68 RI and 1.49 PI.
Authors:
Helena T Nyman; Annemarie T Kristensen; Ib M Skovgaard; Fintan J McEvoy
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association     Volume:  46     ISSN:  1058-8183     ISO Abbreviation:  Vet Radiol Ultrasound     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2005-10-27     Completed Date:  2005-12-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9209635     Medline TA:  Vet Radiol Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  404-10     Citation Subset:  IM    
Affiliation:
Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, Copenhagen, Denmark. hny@kvl.dk
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MeSH Terms
Descriptor/Qualifier:
Animals
Diagnosis, Differential
Dog Diseases / ultrasonography*
Dogs / anatomy & histology*
Lymph Nodes / ultrasonography*
Lymphatic Diseases / ultrasonography,  veterinary*
Lymphatic Metastasis / ultrasonography
Multivariate Analysis
Predictive Value of Tests
Ultrasonography, Doppler, Color / veterinary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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