Document Detail


Characterization of a new bacteriocin produced from a novel isolated strain of Bacillus lentus NG121.
MedLine Citation:
PMID:  16779629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The new bacteriocin is produced from Bacillus lentus NG121 isolated from Khameera - a traditional fermented food from Himachal Pradesh, India which has been reported for the first time in the literature to produce bacteriocin and exhibited very high activity units of 20 x 10(5) AU (Arbitrary Units)/ml. This bacteriocin was partially purified and was further characterized to assess its preservation characteristics. It showed strong antimicrobial activity against the most challenging and serious test indicators like Listeria monocytogens and Staphylococcus aureus. There was a drastic decrease up to 70% in viable cells of the indicators within the first 10 h of adding partially purified bacteriocin thus proving its bactericidal action. It could withstand the high heat of 100 degrees C for 10 min of heating time without losing any activity. A wide range of pH tolerance i.e. from 5.0-10.0 was expressed by this bacteriocin. It was found completely sensitive to proteolytic enzyme trypsin. The unique combination of all the above mentioned characteristics makes the bacteriocin of newly isolated Bacillus lentus NG121, a food grade bacteria, highly desirable for preservation of different food items in the food industry.
Authors:
Nivedita Sharma; G Kapoor; B Neopaney
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Publication Detail:
Type:  Journal Article     Date:  2006-04-25
Journal Detail:
Title:  Antonie van Leeuwenhoek     Volume:  89     ISSN:  0003-6072     ISO Abbreviation:  Antonie Van Leeuwenhoek     Publication Date:    2006 Apr-May
Date Detail:
Created Date:  2006-06-16     Completed Date:  2006-08-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372625     Medline TA:  Antonie Van Leeuwenhoek     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  337-43     Citation Subset:  IM    
Affiliation:
Department of Basic Sciences, Dr. Y.S. Parmar University of Horticulture and Forestry, Nauni, Solan, India. nivea_64@yahoo.co.in
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents* / chemistry,  metabolism,  pharmacology
Bacillus / classification*,  isolation & purification,  metabolism*
Bacteriocins* / chemistry,  metabolism,  pharmacology
Cultural Characteristics
Fermentation
Food Preservation / methods*
Hot Temperature
Hydrogen-Ion Concentration
India
Listeria monocytogenes / drug effects
Microbial Sensitivity Tests
Staphylococcus aureus / drug effects
Triticum / microbiology*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Bacteriocins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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