Document Detail


Characterization of a native polysaccharide hapten from Brucella melitensis.
MedLine Citation:
PMID:  3117696     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The 13C nuclear magnetic resonance spectrum of Brucella melitensis native polysaccharide hapten proved to be very similar to that generated by the O-specific chain (PS) isolated from B. melitensis lipopolysaccharide; that is, to a linear polymer in which the repeating unit is composed of five N-formylperosaminyl residues, one of them being substituted at position C-3 and the other four at position C-2. The serological analysis suggests that the so-called A determinant is present solely in Brucella abortus PS, the M determinant is only in B. melitensis PS, and the extensive cross-reaction observed is due to a determinant shared by both polysaccharides.
Authors:
E Moreno; H Mayer; I Moriyon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Infection and immunity     Volume:  55     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1987-11-25     Completed Date:  1987-11-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2850-3     Citation Subset:  IM    
Affiliation:
Centro de Investigación en Biología Celular y Molecular, Universidad de Costa Rica, San José.
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MeSH Terms
Descriptor/Qualifier:
Antigens, Bacterial / isolation & purification*
Binding, Competitive
Brucella / immunology*
Brucella abortus / immunology
Carbohydrate Sequence
Enzyme-Linked Immunosorbent Assay
Haptens
Magnetic Resonance Spectroscopy
Polysaccharides, Bacterial / immunology*
Yersinia / immunology
Chemical
Reg. No./Substance:
0/Antigens, Bacterial; 0/Haptens; 0/Polysaccharides, Bacterial
Comments/Corrections

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