Document Detail


Characterization of mdcR, a regulatory gene of the malonate catabolic system in Klebsiella pneumoniae.
MedLine Citation:
PMID:  10094715     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Klebsiella pneumoniae mdcR gene, which encodes a LysR-type regulator, was overexpressed in Escherichia coli. Purified MdcR was found to bind specifically to the control region of either the malonate decarboxylase (mdc) genes or mdcR. We have also demonstrated that MdcR is an activator of the expression of the mdc genes, whereas it represses the transcription of the putative control region of mdcR, PmdcR, indicating a negative autoregulatory control.
Authors:
H L Peng; S R Shiou; H Y Chang
Related Documents :
24191945 - Triple trans-splicing aav vectors capable of transferring the coding sequence for full-...
8422995 - Characterization of the gene coding for the rickettsia prowazekii dna primase analogue.
8299955 - Identification of a promoter for the crystal protein-encoding gene cryivb from bacillus...
10488765 - Identification of the sigma c-encoded gene of avian reovirus by nested pcr and restrict...
10743555 - Evaluation of gene prediction software using a genomic data set: application to arabido...
6955785 - Complete sequence analysis of cdna clones encoding rat whey phosphoprotein: homology to...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of bacteriology     Volume:  181     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-04-22     Completed Date:  1999-04-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2302-6     Citation Subset:  IM    
Affiliation:
Institute of Biological Science and Technology, National Chiao Tung University, Hsin Chu, Taiwan, Republic of China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Base Sequence
Carboxy-Lyases / genetics*,  isolation & purification
DNA, Bacterial
Escherichia coli
Gene Expression Regulation, Bacterial
Genes, Bacterial
Klebsiella pneumoniae / enzymology*,  genetics
Malonates / metabolism*
Molecular Sequence Data
Promoter Regions, Genetic
Recombinant Fusion Proteins / genetics,  isolation & purification
Chemical
Reg. No./Substance:
0/DNA, Bacterial; 0/Malonates; 0/Recombinant Fusion Proteins; EC 4.1.1.-/Carboxy-Lyases; EC 4.1.1.-/malonate decarboxylase
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cellular locations of Pseudomonas syringae pv. syringae HrcC and HrcJ proteins, required for harpin ...
Next Document:  Conserved organization in the cps gene clusters for expression of Escherichia coli group 1 K antigen...