Document Detail


Characterization of the inhibition of hepatitis C virus entry by in vitro-generated and patient-derived oxidized low-density lipoprotein.
MedLine Citation:
PMID:  23212706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: oxLDL is a potent pangenotype HCV entry inhibitor that maintains its activity in the context of human serum and targets an early step of HCV entry.
Authors:
Sandra Westhaus; Dorothea Bankwitz; Stefanie Ernst; Katrin Rohrmann; Ilka Wappler; Clemens Agné; Maren Luchtefeld; Bernhard Schieffer; Christoph Sarrazin; Michael P Manns; Thomas Pietschmann; Sandra Ciesek; Thomas von Hahn
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-02-15
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  57     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-23     Completed Date:  2013-07-05     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1716-24     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Association for the Study of Liver Diseases.
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MeSH Terms
Descriptor/Qualifier:
Antigens, CD36 / physiology
Carcinoma, Hepatocellular / pathology,  virology
Cell Line, Tumor
Cells, Cultured
DNA, Viral / genetics
Genotype
Hepacivirus / drug effects,  genetics*,  physiology*
Hepatitis C, Chronic / blood*
Humans
Lipoproteins, LDL / blood,  pharmacology*
Liver Neoplasms / pathology,  virology
Viral Load
Virion / physiology
Virus Replication / drug effects*,  physiology
Chemical
Reg. No./Substance:
0/Antigens, CD36; 0/DNA, Viral; 0/Lipoproteins, LDL; 0/oxidized low density lipoprotein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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