Document Detail

Characterization and in vitro cytocompatibility of an acid-etched titanium surface.
MedLine Citation:
PMID:  20464314     Owner:  NLM     Status:  MEDLINE    
The aims of this study were to characterize the microstructure of a commercially pure titanium (cpTi) surface etched with HCl/H2SO4 (AE-cpTi) and to investigate its in vitro cytocompatibility compared to turned cpTi (T-cpTi). T-cpTi showed a grooved surface and AE-cpTi revealed a surface characterized by the presence of micropits. Surface parameters indicated that the AE-cpTi surface is more isotropic and present a greater area compared to T-cpTi. The oxide film thickness was similar between both surfaces; however, AE-cpTi presented more Ti and O and less C. Osteoblastic cell proliferation, alkaline phosphatase activity, and bone-like nodule formation were greater on T-cpTi than on AE-cpTi. These results show that acid etching treatment produced a surface with different topographical and chemical features compared to the turned one, and such surface modification affected negatively the in vitro cytocompatibility of cpTi as demonstrated by decreasing culture growth and expression of osteoblastic phenotype.
Daniel Rey de Carvalho; Paulo Sérgio Perri de Carvalho; Osvaldo Magro Filho; José Daniel Biasoli de Mello; Márcio Mateus Beloti; Adalberto Luiz Rosa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Brazilian dental journal     Volume:  21     ISSN:  1806-4760     ISO Abbreviation:  Braz Dent J     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-05-13     Completed Date:  2010-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214652     Medline TA:  Braz Dent J     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  3-11     Citation Subset:  D    
Department of Oral and Maxillofacial Surgery, Dental School, Catholic University of Brasília, Brasília, DF, Brazil.
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MeSH Terms
Acid Etching, Dental*
Alkaline Phosphatase / analysis
Alveolar Process / cytology
Biocompatible Materials / chemistry,  pharmacology*
Biological Markers / analysis
Carbon / chemistry
Cell Adhesion / drug effects
Cell Division / drug effects
Cell Proliferation / drug effects
Cell Survival / drug effects
Cells, Cultured
Dental Materials / chemistry,  pharmacology*
Hydrochloric Acid / chemistry
Materials Testing
Microscopy, Electron, Scanning
Osteoblasts / drug effects*
Osteogenesis / drug effects
Photoelectron Spectroscopy
Sulfuric Acids / chemistry
Surface Properties
Titanium / chemistry,  pharmacology*
Reg. No./Substance:
0/Biocompatible Materials; 0/Biological Markers; 0/Dental Materials; 0/Sulfuric Acids; 13463-67-7/titanium dioxide; 7440-32-6/Titanium; 7440-44-0/Carbon; 7647-01-0/Hydrochloric Acid; 7664-93-9/sulfuric acid; EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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