Document Detail

Characterization of a highly polymeric proanthocyanidin fraction from persimmon pulp with strong Chinese cobra PLA(2) inhibition effects.
MedLine Citation:
PMID:  22037569     Owner:  NLM     Status:  Publisher    
Persimmon proanthocyanidin was fractionated on Toyopearl TSK-HW-50-F to yield a fraction with strong inhibition on the catalytic activity and edema-inducing activity and lethality of Chinese cobra PLA(2). Thiolysis suggested that the terminal units included C, EGCG and myricetin, and epicatechin, epigallocatechin, (epi)gallocatechin-3-O-gallate, and (epi)catechin-3-O-gallate occurred as extender units. The mean degree of polymerization was 23.7 MALDI TOF/MS, thioly-HPLC, FTIR and circular dichroism (CD) analyses showed that the fraction had high prodelphinidin content (55%) and a very high degree of 3-O-galloylation (92%). A type linkage is dominant in it and it had 4β linkage of the flavanyl substituent and 4R absolute configuration.
Shu-Fen Xu; Bo Zou; Jie Yang; Ping Yao; Chun-Mei Li
Related Documents :
16880539 - Structure of staphylococcus aureus cytidine monophosphate kinase in complex with cytidi...
22187439 - Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis.
19860729 - Assays for identification of hsp90 inhibitors and biochemical methods for discriminatin...
11790099 - Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphono...
21708939 - Metal fluoride complexes of na,k-atpase: characterization of fluoride-stabilized phosph...
19141289 - Structure of the pseudokinase vrk3 reveals a degraded catalytic site, a highly conserve...
1930199 - Separation of the two domains of human mucus proteinase inhibitor: inhibitory activity ...
9632679 - Unfolding of diphtheria toxin. identification of hydrophobic sites exposed on lowering ...
16536459 - Nmr and crystallographic characterization of adventitious borate binding by trypsin.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-20
Journal Detail:
Title:  Fitoterapia     Volume:  -     ISSN:  1873-6971     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  16930290R     Medline TA:  Fitoterapia     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier B.V.
College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A new alkaloid from Fritillaria ussuriensis Maxim.
Next Document:  Dispensable role for 4-1BB and 4-1BBL in development of vaccinia virus-specific CD8 T cells.