| Characterization of a fucoarabinogalactan, the main polysaccharide from the gum exudate of Croton urucurana. | |
| | |
MedLine Citation:
|
PMID: 12193018 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A fucoarabinogalactan (CU-1), the main component of the gum exudate of the medicinal plant Croton urucurana, has been isolated by precipitation and subsequent dialysis and finally purified by ion-exchange chromatography. The estimated average molecular weight of CU-1 by gel permeation chromatography was approximately 2.48 x 10(6) Da. CU-1 was found to contain 1.0% proteins and 93.7% total sugars, mainly fucose, arabinose, and galactose (molar ratio: 7.8, 8.1, 19.0), and minor quantities of mannose, xylose, glucose, and uronic acids (molar ratio: 2.2, 1.0, 0.3, 3.0). Among the uronic acids, glucuronic acid was identified and the presence of mannuronic acid could be also presumed. Methylation analysis of this polysaccharide revealed high proportions of 1,3-linked, 1,2,3-linked, and 1,2,3,6-linked galactose, 1-linked fucose, and 1-linked arabinose. This suggests that CU-1 is constituted by a principal skeleton of (1-->3)-linked galactopyranose units, with some of these galactose units branched at the 2-position or at both the 2- and 6-positions, and with mainly terminal fucopyranosyl and arabinofuranosyl residues in the side chains. This is the first report on the polysaccharide constitution of a gum exudate from a Croton species. |
| | |
Authors:
|
Begoña Milo; Ester Risco; Roser Vila; José Iglesias; Salvador Cañigueral |
Related Documents
:
|
3926758 - Structural study on teichoic acids of listeria monocytogenes types 4a and 4d. 11179968 - Structural study of n-linked oligosaccharides of human intercellular adhesion molecule-... 3017918 - Serospecific antigens of legionella pneumophila. 6185428 - Antigenic determinant of the lancefield group h antigen of streptococcus sanguis. 10712548 - Import of lyso-phosphatidylcholine into chloroplasts likely at the origin of eukaryotic... 2903228 - Interaction of vitamin e and its model compounds with unsaturated fatty acids in homoge... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of natural products Volume: 65 ISSN: 0163-3864 ISO Abbreviation: J. Nat. Prod. Publication Date: 2002 Aug |
Date Detail:
|
Created Date: 2002-08-23 Completed Date: 2002-10-21 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7906882 Medline TA: J Nat Prod Country: United States |
Other Details:
|
Languages: eng Pagination: 1143-6 Citation Subset: IM |
Affiliation:
|
Unitat de Farmacologia i Farmacognòsia, Facultat de Farmàcia, Universitat de Barcelona, Avinguda Diagonal, 643, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amino Acids
/
analysis Croton / chemistry* Galactans / chemistry*, isolation & purification* Gas Chromatography-Mass Spectrometry Hydrolysis Methylation Paraguay Plants, Medicinal / chemistry* |
| Chemical | |
Reg. No./Substance:
|
0/Amino Acids; 0/Galactans; 0/fucoarabinogalactan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Design and synthesis of a combinatorial chemistry library of 7-acyl, 10-acyl, and 7,10-diacyl analog...
Next Document: Naturally occurring cembranes from an Australian sarcophyton species.