Document Detail


Characterization of ergocalciferol loaded solid lipid nanoparticles.
MedLine Citation:
PMID:  22260120     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PRACTICAL APPLICATION: Solid lipid nanoparticles (SLNs) were used in this study to encapsulate vitamin D₂, a vitamin important for bone health. It was found that as the concentration of vitamin D₂ increased in the lipid phase of SLN dispersion, the clarity of the dispersion increased. Also, with increased vitamin D₂ concentration, the stability of lipid crystal structure was affected in a way that indicates higher capacity of lipid to incorporate the vitamin molecules and hence to protect them better from oxygen and light. This vitamin loaded SLNs may offer alternatives to milk and margarine as a source of vitamin D.
Authors:
Mandar R Patel; M Fernanda San Martin-Gonzalez
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of food science     Volume:  77     ISSN:  1750-3841     ISO Abbreviation:  J. Food Sci.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-01-20     Completed Date:  2012-06-12     Revised Date:  2013-07-15    
Medline Journal Info:
Nlm Unique ID:  0014052     Medline TA:  J Food Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  N8-13     Citation Subset:  IM    
Copyright Information:
© 2011 Institute of Food Technologists®
Affiliation:
Department of Food Science, Purdue University, West Lafayette, IN 47907, USA.
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MeSH Terms
Descriptor/Qualifier:
Calorimetry, Differential Scanning
Ergocalciferols / administration & dosage*,  chemistry*
Excipients / chemistry
Food, Fortified / analysis
Hot Temperature
Lipids / chemistry*
Microscopy, Electron, Transmission
Nanoparticles / chemistry*,  ultrastructure
Nephelometry and Turbidimetry
Particle Size
Physicochemical Phenomena
Polysorbates / chemistry
Transition Temperature
Triglycerides / chemistry
Chemical
Reg. No./Substance:
0/Ergocalciferols; 0/Excipients; 0/Lipids; 0/Polysorbates; 0/Triglycerides; D133ZRF50U/tripalmitin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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