Document Detail


Characterization of cosmetic cream with Mesembryanthemum crystallinum plant extract: influence of formulation composition on physical stability and anti-oxidant activity.
MedLine Citation:
PMID:  19099545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cosmetic or pharmaceutical composition containing superoxide dismutase (SOD) was usually used in topical administration, particularly, in fighting against skin ageing and in the protection of the skin against radiation exposure. Mesembryanthemum crystallinum is a halophyte plant widely used in the traditional medicine, characterized by the presence of anti-oxidants enzymes in responses to abiotic stresses. In the present study, we prepared a formulation with M. crystallinum extract characterized by naturally occurring SOD and catalase in association with other anti-oxidants molecules. The SOD activity was measured by 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl-tetrazolium bromide/riboflavin method, catalase by colorimetric method and the total anti-radical activity was measured by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) method. Formulations contain a significant SOD activity (8.33 U mg(-1)), a catalase activity (0.5 x 10(7) UC) and an anti-radical activity (30% of DPPH inhibition). The formulation storage (15 days at 4 degrees C) showed a marked loss of total anti-oxidant capacity. The addition of the M. crystallinum extract induced also a reduction in formulation viscosity and pH.
Authors:
I Bouftira; C Abdelly; S Sfar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cosmetic science     Volume:  30     ISSN:  1468-2494     ISO Abbreviation:  Int J Cosmet Sci     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-22     Completed Date:  2009-02-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007161     Medline TA:  Int J Cosmet Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  443-52     Citation Subset:  IM    
Affiliation:
Laboratory of Galenic Pharmacy, Faculty of Pharmacy of Monastir, Monastir, Tunisia. ibtissem.bouftira@laposte.net
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MeSH Terms
Descriptor/Qualifier:
Antioxidants / chemistry*,  pharmacology
Catalase / chemistry*,  pharmacology
Emollients / chemistry*
Free Radical Scavengers / chemistry,  pharmacology
Hydrogen-Ion Concentration
Mesembryanthemum / enzymology*
Plant Extracts / chemistry,  pharmacology
Plant Leaves / enzymology
Superoxide Dismutase / chemistry*,  pharmacology
Viscosity
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Emollients; 0/Free Radical Scavengers; 0/Plant Extracts; EC 1.11.1.6/Catalase; EC 1.15.1.1/Superoxide Dismutase

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