Document Detail

Characterization of conduction recovery after pulmonary vein isolation using the "single big cryoballoon" technique.
MedLine Citation:
PMID:  20129295     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Pulmonary vein isolation using the cryoballoon technique (CB-PVI) has evolved into a simple and safe alternative for point-by-point radiofrequency ablation. Systematic analysis of conduction recovery occurring after CB-PVI and causing recurrent atrial fibrillation has not yet been performed. OBJECTIVE: The purpose of this study was to analyze conduction recovery after PVI using the single big (28-mm) cryoballoon technique. METHODS: Twenty-six patients with recurrent atrial tachyarrhythmia after previous CB-PVI underwent repeat ablation. Pulmonary vein (PV) reisolation was performed by antral irrigated radiofrequency ablation using electroanatomic mapping. For analysis of the location of conduction gaps, the ipsilateral LA-PV junction was divided into six equally distributed segments. RESULTS: PV reconduction frequently occurred into multiple (>2) PVs (54% patients). Conduction gaps could be abolished by single point ablation in 63% (lateral) and 41% (septal) of patients or by incomplete circular lesions in the remaining patients. A significantly higher number of patients exhibited conduction recovery at inferior segments (85% lateral, 77% septal) compared with superior segments (42% lateral, 31% septal). Furthermore, the ridge between PV ostia and left atrial appendage (LAA) was highly associated with reconduction into lateral PVs (81% of patients). Retrospective analysis of the initial CB-PVI-procedure revealed lower freezing temperatures at superior than inferior PVs as well as sharp catheter angulations with loss of central cryoballoon alignment to reach inferior PVs. CONCLUSION: Conduction recovery after CB-PVI occurs at a high incidence at inferior sites around ipsilateral PV ostia and the LAA-PV ridge. Modifications of the technique to ensure optimal balloon-tissue contact at predilection sites may improve long-term success rates.
Alexander F?rnkranz; K R Julian Chun; Dieter Nuyens; Andreas Metzner; Ilka K?ster; Boris Schmidt; Feifan Ouyang; Karl-Heinz Kuck
Related Documents :
17938285 - Prediction of atrial fibrillation via atrial electromechanical interval after coronary ...
19591075 - Changes in amniotic fluid concentration of thrombin-antithrombin iii complexes in patie...
15623545 - Linear cryoablation of the left atrium versus pulmonary vein cryoisolation in patients ...
2030555 - Atrial fibrillation and atrial vulnerability in the wolff-parkinson-white syndrome.
8769395 - The relevance of somatostatin receptor expression in malignant lymphomas.
3714345 - Cold air provocation of airway hyperreactivity in patients with cystic fibrosis.
Publication Detail:
Type:  Journal Article     Date:  2009-11-10
Journal Detail:
Title:  Heart rhythm : the official journal of the Heart Rhythm Society     Volume:  7     ISSN:  1556-3871     ISO Abbreviation:  Heart Rhythm     Publication Date:  2010  
Date Detail:
Created Date:  2010-02-04     Completed Date:  2010-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101200317     Medline TA:  Heart Rhythm     Country:  United States    
Other Details:
Languages:  eng     Pagination:  184-90     Citation Subset:  IM    
Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angioplasty, Balloon / methods*
Atrial Fibrillation / physiopathology,  radiography,  surgery*
Catheter Ablation / methods*
Coronary Angiography
Cryosurgery / methods*
Electrophysiologic Techniques, Cardiac
Middle Aged
Pulmonary Veins / physiopathology,  surgery*
Treatment Outcome
Comment In:
Heart Rhythm. 2010;7(2):191-2   [PMID:  20129296 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Inadvertent electrical isolation of the left atrial appendage during catheter ablation of persistent...
Next Document:  Diagnostic utility of bipolar precordial leads during ajmaline testing for suspected Brugada syndrom...