| Characterization of a circular plasmid from Borrelia burgdorferi, etiologic agent of Lyme disease. | |
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MedLine Citation:
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PMID: 3183006 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Borrelia burgdorferi, the etiologic agent of Lyme disease, was recently shown to contain plasmid DNA. Two plasmid species have been described in strain CT1, a Wisconsin tick isolate: a 9.2-kilobase entity; and a larger, 70-kilobase entity. Characterization of the 9.2-kilobase entity by using DNase I and restriction endonucleases demonstrated that the plasmid is supercoiled and exists as a stable dimer in this strain. The role played by the plasmid in B. burgdorferi is unknown. |
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Authors:
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F W Hyde; R C Johnson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of clinical microbiology Volume: 26 ISSN: 0095-1137 ISO Abbreviation: J. Clin. Microbiol. Publication Date: 1988 Oct |
Date Detail:
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Created Date: 1988-12-01 Completed Date: 1988-12-01 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 7505564 Medline TA: J Clin Microbiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2203-5 Citation Subset: IM |
Affiliation:
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Department of Microbiology, University of Minnesota, Minneapolis 55455. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Borrelia
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genetics* DNA, Bacterial / analysis Humans Lyme Disease / etiology* Plasmids* |
| Grant Support | |
ID/Acronym/Agency:
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AR34744/AR/NIAMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/DNA, Bacterial |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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