Document Detail


Characterization of the brachial artery shear stress following walking exercise.
MedLine Citation:
PMID:  18593799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Habitual exercise provides repeated episodes of elevated vascular shear stress (SS), which may be a mechanism for repair of endothelial dysfunction in disease. Our aim was to determine the brachial artery SS during the 3-hour period following single bouts of low, moderate, and high-intensity walking exercise. In a randomized crossover design, 14 men walked for 45 minutes on a treadmill at 25%, 50% and 75% of VO2peak separated by 2-7 days. Using Doppler ultrasonography, brachial artery SS was assessed immediately after exercise and then hourly for 3 hours. High-intensity walking elicited greater (p<0.05) post-exercise SS compared with low and moderate intensity. In addition, a 3x4 (intensity x time) ANOVA indicated an absence of interaction (p=0.369) and a decline in post-exercise SS over time (p<0.0001) which was abolished after 2 hours. Thus, we found that brachial artery SS is greatest following high-intensity walking and that the rate of decline in SS is similar across all walking intensities.
Authors:
Jaume Padilla; Ryan A Harris; Lawrence D Rink; Janet P Wallace
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Vascular medicine (London, England)     Volume:  13     ISSN:  1358-863X     ISO Abbreviation:  Vasc Med     Publication Date:  2008  
Date Detail:
Created Date:  2008-07-02     Completed Date:  2008-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610930     Medline TA:  Vasc Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  105-11     Citation Subset:  IM    
Affiliation:
Clinical Exercise Physiology Laboratory, Department of Kinesiology, Indiana University, Bloomington, IN 47405, USA. jpadilla@indiana.edu
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MeSH Terms
Descriptor/Qualifier:
Aged
Brachial Artery / physiology*,  ultrasonography
Cross-Over Studies
Endothelium, Vascular / physiology
Exercise Test
Humans
Male
Middle Aged
Oxygen Consumption
Random Allocation
Stress, Mechanical
Time Factors
Ultrasonography, Doppler
Walking*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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