Document Detail

Characterization of black raspberry functional food products for cancer prevention human clinical trials.
MedLine Citation:
PMID:  24345009     Owner:  NLM     Status:  Publisher    
Our team is designing and fully characterizing black raspberries (BRB) food products suitable for long-term cancer prevention studies. The processing, scale up and storage effect on the consistency, quality, bioactive stability and sensory acceptability of two BRB delivery systems of varying matrices is presented. BRB dosage, pH, water activity and texture were consistent in the scale-up production. Confections retained > 90% of anthocyanins and ellagitannin after processing. Nectars had > 69% of anthocyanins and > 66% of ellagitannin retention which varied with BRB dosage due to the processing difference. Texture remained unchanged during storage. BRB products consumed in a prostate cancer clinical trial were well accepted in sensory tests. Thus, this study demonstrates that two different BRB foods can be formulated to meet quality standards with a consistent bioactive pattern and successfully scaled up for a large human clinical trial focusing on cancer risk and other health outcomes.
Junnan Gu; Jennifer H Ahn-Jarvis; Ken M Riedl; Steven J Schwartz; Steven K Clinton; Yael Vodovotz
Related Documents :
15332449 - Lack of evidence for a marked endogenous component determining food intake in humans du...
6783069 - Availability of lysine in vegetable protein concentrates as determined by the slope-rat...
20660799 - Intra-articular microparticles for drug delivery to the tmj.
16393709 - Food intake in healthy young adults: effects of time pressure and social factors.
3446449 - Usual meal times in relation to age, sex, work activity and morningness-eveningness.
8126639 - Use of frozen meals by and food preferences of various age groups of adults.
20442769 - Food insecurity as a barrier to sustained antiretroviral therapy adherence in uganda.
10065729 - The in vitro elution characteristics of antibiotic-loaded cmw and palacos-r bone cements.
17952639 - Distribution of peripherally injected peptide yy ([125i] pyy (3-36)) and pancreatic pol...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-12-18
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Editorial Comment on END-2013-0440.OR.R1.
Next Document:  An Unusual Challenge in Performing Sphenopalatine Ganglion Block with Enlarged Coronoid Process: Jac...