Document Detail

Characterization and bioavailability of vitamin B12-compounds from edible algae.
MedLine Citation:
PMID:  12656203     Owner:  NLM     Status:  MEDLINE    
Substantial amounts of vitamin B12 were found in some edible algae (green and purple lavers) and algal health food (chlorella and spirulina tablets) using the Lactobacillus delbrueckii subsp. lactis ATCC7830 microbiological assay method. Corrinoid-compounds were purified and characterized from these algae to clarify the chemical properties and bioavailability of the algal vitamin B12. True vitamin B12 is the predominate cobamide of green and purple lavers and chlorella tablets. Feeding the purple laver to vitamin B12-deficient rats significantly improved the vitamin B12 status. The results suggest that algal vitamin B12 is a bioavailable source for mammals. Pseudovitamin B12 (an inactive corrinoid) predominated in the spirulina tablets, which are not suitable for use as a vitamin B12 source, especially for vegetarians. algal health food, bioavailability, cobalamin, edible algae, vitamin B12
Fumio Watanabe; Shigeo Takenaka; Hiromi Kittaka-Katsura; Shuhei Ebara; Emi Miyamoto
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of nutritional science and vitaminology     Volume:  48     ISSN:  0301-4800     ISO Abbreviation:  J. Nutr. Sci. Vitaminol.     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2003-03-26     Completed Date:  2003-07-16     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0402640     Medline TA:  J Nutr Sci Vitaminol (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  325-31     Citation Subset:  IM    
Department of Health Science, Kochi Women's University, Kochi 780-8515, Japan.
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MeSH Terms
Algae / metabolism*
Biological Availability
Vitamin B 12 / isolation & purification*,  pharmacokinetics*
Vitamin B 12 Deficiency / diet therapy*
Reg. No./Substance:
68-19-9/Vitamin B 12

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