| Characterization of bacterial etiologic agents of biofilm formation in medical devices in critical care setup. | |
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MedLine Citation:
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PMID: 22312484 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background. Biofilms contaminate catheters, ventilators, and medical implants; they act as a source of disease for humans, animals, and plants. Aim. Critical care units of any healthcare institute follow various interventional strategies with use of medical devices for the management of critical cases. Bacteria contaminate medical devices and form biofilms. Material and Methods. The study was carried out on 100 positive bacteriological cultures of medical devices which were inserted in hospitalized patients. The bacterial isolates were processed as per microtitre plate. All the isolates were subjected to antibiotic susceptibility testing by VITEK 2 compact automated systems. Results. Out of the total 100 bacterial isolates tested, 88 of them were biofilm formers. A 16-20-hour incubation period was found to be optimum for biofilm development. 85% isolates were multidrug resistants and different mechanisms of bacterial drug resistance like ESBL, carbapenemase, and MRSA were found among isolates. Conclusion. Availability of nutrition in the form of glucose enhances the biofilm formation by bacteria. Time and availability of glucose are important factors for assessment of biofilm progress. It is an alarm for those who are associated with invasive procedures and indwelling medical devices especially in patients with low immunity. |
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Authors:
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Sangita Revdiwala; Bhaumesh M Rajdev; Summaiya Mulla |
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Publication Detail:
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Type: Journal Article Date: 2012-01-24 |
Journal Detail:
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Title: Critical care research and practice Volume: 2012 ISSN: 2090-1313 ISO Abbreviation: Crit Care Res Pract Publication Date: 2012 |
Date Detail:
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Created Date: 2012-02-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101539357 Medline TA: Crit Care Res Pract Country: Egypt |
Other Details:
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Languages: eng Pagination: 945805 Citation Subset: - |
Affiliation:
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Department of Microbiology, Government Medical College, Surat, Veer Narmad South Gujarat University, Surat 395001, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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