Document Detail


Characterization of atrial fibrillation in man: studies following open heart surgery.
MedLine Citation:
PMID:  95635     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The nature of localized atrial activation during atrial fibrillation was characterized in 34 patients following open heart surgery. Bipolar atrial electrograms (AEG) recorded in each patient with atrial fibrillation exhibited a myriad of sizes, shapes, polarities, amplitudes, and beat-to-beat intervals. On the basis of the AEG morphology and the nature of its baseline, we have classified the recordings into four Types. Type I was characterized by discrete AEG complexes separated by an isoelectric baseline free of perturbation, Type II by discrete AEG complexes but with perturbations of the baseline between complexes, Type III by AEGs which failed to demonstrate either discrete complexes or isoelectric intervals, and Type IV in which AEGs of Type III alternated with periods characteristic of Type I and/or Type II. In 22 patients, the AEGs were recorded a second time, and in 11 of these patients the type of atrial fibrillation changed between the first and second recording period. An atrial flutter-fibrillation pattern in the ECG was associated with a relatively ordered atrial activation pattern and a relatively slow atrial rate. Human atrial fibrillation is not an electrophysiologically homogeneous process when compared among different patients or ad seriatim in the same patient.
Authors:
J L Wells; R B Karp; N T Kouchoukos; W A MacLean; T N James; A L Waldo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  1     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1978 Oct 
Date Detail:
Created Date:  1984-08-30     Completed Date:  1984-08-30     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  426-38     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Atrial Fibrillation / classification,  physiopathology*
Cardiac Surgical Procedures*
Electrocardiography / instrumentation,  methods
Electrodes, Implanted
Heart Diseases / drug therapy,  physiopathology,  surgery
Humans
Middle Aged
Postoperative Complications / physiopathology
Grant Support
ID/Acronym/Agency:
5P50HL17667/HL/NHLBI NIH HHS; HL11,310/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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