Document Detail

Characterization of the Hanganutziu-Deicher (serum-sickness) antigen as gangliosides containing n-glycolylneuraminic acid.
MedLine Citation:
PMID:  78906     Owner:  NLM     Status:  MEDLINE    
Gangliosides that possess the same sugar sequence but differing in the type of sialic acid (N-acetyl- or N-glycolylneuraminic acid) were compared for their reactivity with Hanganutziu-Deicher ('serum sickness') antibodies by double-diffusion gel precipitation tests. Only N-glycolylneuraminic acid containing gangliosides formed precipitation lines with Hanganutziu-Deicher antibodies, thus suggesting that Hanganutziu-Deicher antigens are gangliosides that contain N-glycolylneuraminic acid.
J M Merrick; K Zadarlik; F Milgrom
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International archives of allergy and applied immunology     Volume:  57     ISSN:  0020-5915     ISO Abbreviation:  Int. Arch. Allergy Appl. Immunol.     Publication Date:  1978  
Date Detail:
Created Date:  1978-09-29     Completed Date:  1978-09-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404561     Medline TA:  Int Arch Allergy Appl Immunol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  477-80     Citation Subset:  IM    
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MeSH Terms
Antibody Specificity
Gangliosides / immunology*
Serum Sickness / immunology*
Sialic Acids*
Reg. No./Substance:
0/Antigens; 0/Epitopes; 0/Gangliosides; 0/Sialic Acids

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