| Characterization of Fc receptors associated with human malignant tumors. | |
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MedLine Citation:
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PMID: 7464156 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fc receptors from human tumors were isolated by sucrose gradient fractionation and affinity chromatography techniques. The isolated Fc receptors showed specificity for IgG(Fc) in the closed chamber hemadsorption technique and also in the inhibition experiments using radiolabeled Fc receptors. The results indicate that Fc receptors isolated from tumor tissue are similar to Fc receptors isolated from normal human spleen, dog macrophages, and peripheral white blood cells (WBCs). However, the Fc receptors isolated from macrophages are more potent inhibitors when compared with tumor, spleen, and peripheral WBC Fc receptors. Also, Fc receptors isolated from the various sources are independent of species specificity. |
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Authors:
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E C Krishnan; L Krishnan; W R Jewell |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of surgical oncology Volume: 16 ISSN: 0022-4790 ISO Abbreviation: J Surg Oncol Publication Date: 1981 |
Date Detail:
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Created Date: 1981-04-24 Completed Date: 1981-04-24 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0222643 Medline TA: J Surg Oncol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 179-88 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies
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analysis Antibody Affinity Binding, Competitive Centrifugation, Density Gradient Chromatography, Affinity Humans Immunoglobulin Fc Fragments / analysis* Immunoglobulin G / analysis Neoplasms / immunology* Species Specificity |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 0/Immunoglobulin Fc Fragments; 0/Immunoglobulin G |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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